WWE Friday Night SmackDown on the USA Network | September 12th, 2025 — The Episode Preview:

Drew McIntyre battles against his long-time rival Randy Orton in a Singles Match. Don't miss WWE Friday Night SmackDown at 8:00 PM ET / 5:00 PM PT on the USA Network. (Photo by WWE)

The September 12th Episode of WWE Friday Night SmackDown — The Episode Rundown:

• Tiffany Stratton defends her title against Jade Cargill in a highly anticipated SummerSlam rematch. Cargill is determined to regain the WWE Women's Championship, while Stratton touts her undefeated 2025 streak. Who will prevail in this rematch?

• Also tonight, fierce rivals Drew McIntyre and Randy Orton meet in singles competition, after recent battles at WWE Saturday Night Main Event and SummerSlam. Who will emerge victorious in this major PLE matchup?

• Sami Zayn has got the blessing from John Cena to make his own WWE United States Open Challenge Weekly Challenges. Who’ll step up to Sami Zayn and challenge him for his WWE United States Championship tonight on Friday Night SmackDown?

The Matches Announced for the September 12th Episode of WWE Friday Night SmackDown:

1. Tiffany Stratton (c) vs. Jade Cargill in a WWE Women’s Title Match.

2. Drew McIntyre vs. Randy Orton in a Singles Match.

3. Sami Zayn WWE United States Championship Open Challenge Match.